The wheel of the Mouse 
rotation -> Zoom IN and Zoom Out 
pressed -> Pan in the active window 
double-click -> Zoom Extension in the Active window 

To use the CTRL key for the Zoom and Pan commands (SilicaCAD 2016 and newer versions), you need to enable Mouse Advanced Functions. 
These settings can be found in the menu Express -> Mouse Advanced Functions (variable CTRLMOUSE) 
CTRL + Left mouse button pressed -> 3D orbit in the window Enabled 
CTRL + SHIFT + Left Mouse button pressed -> Zoom IN and Zoom Out the window 
CTRL + SHIFT + Right Mouse button pressed -> Pan in the Active window 
SHIFT + mouse-> Pan in the Active window